This hearty Chicken & Biscuit Casserole brings together tender shredded chicken, vibrant vegetables, and fluffy golden biscuits in one comforting dish. Perfect for busy weeknights or cozy family dinners, this recipe transforms simple ingredients into a soul-warming meal that’s sure to become a household favorite. The creamy chicken base topped with buttery biscuits creates the ultimate comfort food experience.
Ingredients
- 2 cups cooked chicken, shredded
- 1 can (10.5 oz) cream of chicken soup
- 1 cup chicken broth
- 1 cup frozen mixed vegetables (peas, carrots, corn)
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- Salt and pepper to taste
- 1 can (16.3 oz) refrigerated biscuit dough
- 1/2 cup shredded cheddar cheese (optional)
- Fresh parsley for garnish (optional)
Instructions
- Preheat oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken, cream of chicken soup, chicken broth, frozen mixed vegetables, garlic powder, onion powder, salt, and pepper. Mix until well combined.
- Pour the chicken mixture into a greased 9×13 inch baking dish, spreading it evenly.
- Open the can of biscuit dough and separate the biscuits. Cut each biscuit into quarters and arrange them evenly over the chicken mixture.
- If desired, sprinkle shredded cheddar cheese on top of the biscuits for added flavor.
- Bake in the preheated oven for 25-30 minutes, or until the biscuits are golden brown and cooked through.
- Remove from the oven and let cool for a few minutes. Garnish with fresh parsley before serving.
Variations
- Creamy Mushroom & Herb Version – Replace cream of chicken soup with cream of mushroom soup and add 1 cup sliced fresh mushrooms and 1 tablespoon fresh thyme to the chicken mixture for an earthy, aromatic twist.
- Cheesy Broccoli Chicken Casserole – Substitute mixed vegetables with 2 cups fresh or frozen broccoli florets and increase cheddar cheese to 1 cup, mixing half into the chicken base and sprinkling the rest on top.
- Southwest Style – Add 1 can drained black beans, 1 cup corn, 1 diced bell pepper, and 1 teaspoon cumin to the mixture, then top with pepper jack cheese and serve with fresh cilantro and lime wedges.
Cooking Notes
- Temperature Check – Ensure biscuits reach an internal temperature of 190°F and the chicken mixture is heated through to 165°F before serving to guarantee food safety and perfect texture.
- Prevent Soggy Bottoms – Pat the chicken dry before mixing and avoid adding extra liquid beyond what’s called for, as excess moisture can prevent the biscuits from cooking properly on the bottom.
- Even Browning – Arrange biscuit quarters with space between them to allow proper air circulation, and rotate the dish halfway through baking if your oven has hot spots for uniform golden color.
Serving Suggestions
- Fresh Garden Salad – Pair with a crisp mixed greens salad dressed with light vinaigrette to balance the richness of the casserole and add fresh vegetables to the meal.
- Honey Butter Cornbread – Serve alongside warm cornbread with honey butter for a true Southern comfort food experience that complements the biscuit topping beautifully.
- Roasted Seasonal Vegetables – Accompany with roasted Brussels sprouts, green beans, or asparagus seasoned with garlic and herbs to add color and nutritional variety to the plate.
Tips
- Make-Ahead Magic – Assemble the entire casserole up to 24 hours in advance, cover tightly, and refrigerate. Add 5-10 extra minutes to baking time when cooking from cold.
- Leftover Transformation – Use leftover turkey, rotisserie chicken, or even cooked ground chicken as protein alternatives, adjusting seasoning as needed to maintain flavor balance.
- Freezer-Friendly Option – This casserole freezes well for up to 3 months. Wrap tightly in foil and plastic wrap, then thaw overnight in refrigerator before reheating at 300°F until warmed through.
Prep Time:
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Total Time: 40 minutes
Nutritional Information (Per Serving)
- Calories: 320 kcal
- Protein: 26g
- Sodium: 890mg
Frequently Asked Questions
- Can I use homemade biscuits instead of refrigerated dough? – Absolutely! Prepare your favorite biscuit recipe and drop spoonfuls of dough over the chicken mixture, or roll and cut into pieces. Baking time may need slight adjustment depending on your dough’s thickness.
- How do I store and reheat leftovers? – Store covered in the refrigerator for up to 3 days. Reheat individual portions in the microwave for 1-2 minutes, or warm the entire dish in a 300°F oven for 15-20 minutes until heated through.
- Can I make this casserole dairy-free? – Yes! Use dairy-free cream soup, plant-based milk or broth, and omit the cheese or substitute with dairy-free alternatives. The biscuits can be replaced with dairy-free versions available in most grocery stores.
- What’s the best way to prevent the biscuits from getting soggy? – Make sure your chicken mixture isn’t too watery by draining excess liquid, and don’t overlap the biscuit pieces. Bake immediately after assembly, and avoid covering the dish during baking to maintain the crispy biscuit tops.
Conclusion
This Chicken & Biscuit Casserole delivers everything you want in a comfort food classic – tender chicken, flavorful vegetables, and golden, fluffy biscuits all baked together in one satisfying dish. With its simple preparation and crowd-pleasing flavors, it’s the perfect solution for busy weeknights when you want something homemade and hearty. Whether you stick to the original recipe or try one of the delicious variations, this casserole is sure to become a regular in your dinner rotation, bringing warmth and comfort to your family table.
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Chicken & Biscuit Casserole
- Total Time: 40 minutes
- Yield: 6 servings 1x
Description
This hearty Chicken & Biscuit Casserole brings together tender shredded chicken, vibrant vegetables, and fluffy golden biscuits in one comforting dish. Perfect for busy weeknights or cozy family dinners, this recipe transforms simple ingredients into a soul-warming meal that’s sure to become a household favorite. The creamy chicken base topped with buttery biscuits creates the ultimate comfort food experience.
Ingredients
Scale
- 2 cups cooked chicken, shredded
- 1 can (10.5 oz) cream of chicken soup
- 1 cup chicken broth
- 1 cup frozen mixed vegetables (peas, carrots, corn)
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- Salt and pepper to taste
- 1 can (16.3 oz) refrigerated biscuit dough
- 1/2 cup shredded cheddar cheese (optional)
- Fresh parsley for garnish (optional)
Instructions
- Preheat oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken, cream of chicken soup, chicken broth, frozen mixed vegetables, garlic powder, onion powder, salt, and pepper. Mix until well combined.
- Pour the chicken mixture into a greased 9×13 inch baking dish, spreading it evenly.
- Open the can of biscuit dough and separate the biscuits. Cut each biscuit into quarters and arrange them evenly over the chicken mixture.
- If desired, sprinkle shredded cheddar cheese on top of the biscuits for added flavor.
- Bake in the preheated oven for 25-30 minutes, or until the biscuits are golden brown and cooked through.
- Remove from the oven and let cool for a few minutes. Garnish with fresh parsley before serving.
Notes
- Use rotisserie chicken for convenience, or cook chicken breasts and shred them yourself
- Feel free to substitute with your favorite frozen vegetable mix
- For extra richness, add a tablespoon of butter to the chicken mixture
- Leftover casserole reheats well in the oven at 300°F for 15-20 minutes
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Category: Main Dish
- Method: Baking
- Cuisine: American
Nutrition
- Serving Size: 1 portion
- Calories: 320 kcal
- Sugar: 4g
- Sodium: 890mg
- Fat: 12g
- Saturated Fat: 4g
- Unsaturated Fat: 6g
- Trans Fat: 0g
- Carbohydrates: 28g
- Fiber: 3g
- Protein: 26g
- Cholesterol: 65mg
Keywords: chicken casserole, biscuit topping, comfort food, family dinner, one-dish meal