This Meatloaf Casserole is pure cozy comfort food a tender, juicy meatloaf base baked in a casserole dish and finished with a sweet‑savory ketchup glaze. It’s easy enough for a busy weeknight, yet satisfying and nostalgic enough to serve when you’re craving a classic homestyle dinner.
Ingredients
- 1 pound ground beef (85–90% lean)
- 1 cup breadcrumbs (plain or Italian-style
- 1/2 cup onion, finely chopped
- 1/2 cup bell pepper, finely chopped (any color)
- 2 cloves garlic, minced
- 1/2 cup milk
- 1 large egg
- 1 tablespoon Worcestershire sauce
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- 1/2 teaspoon dried thyme
- 1/2 cup ketchup
- 1/4 cup brown sugar
Instructions

- Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish and set aside.
- In a large mixing bowl, combine the ground beef, breadcrumbs, onion, bell pepper, garlic, milk, egg, Worcestershire sauce, salt, black pepper, and dried thyme.
- Use clean hands or a large spoon to mix until everything is evenly combined, being careful not to overmix so the meatloaf stays tender.
- Transfer the meat mixture to the prepared baking dish and shape it into a loaf down the center, leaving space around the sides for even cooking.
- In a small bowl, stir together the ketchup and brown sugar until smooth. Spread this glaze evenly over the top of the meatloaf loaf.
- Bake in the preheated oven for about 1 hour, or until the meatloaf is cooked through and reaches an internal temperature of 160°F (70°C) in the center.
- Remove from the oven and let the meatloaf casserole rest for 10 minutes to allow the juices to redistribute.
- Slice and serve warm with your favorite sides.
Variation
- Swap up to half of the ground beef for ground pork or turkey for a lighter, slightly different flavor.
- Top the meatloaf casserole with a layer of mashed potatoes during the last 15–20 minutes of baking for a shepherd’s pie–style twist.
- Stir 1 cup of shredded cheddar or mozzarella into the meat mixture or sprinkle on top during the last 10 minutes for a cheesy meatloaf casserole.
Cooking Notes
- Avoid overmixing the meat stop as soon as everything looks evenly combined to keep the texture tender, not dense.
- Baking the meatloaf in a 9×13 dish lets more edges caramelize, giving extra flavor and a slightly crisper exterior.
- Resting the meatloaf for 10 minutes before slicing is key; it keeps the slices from falling apart and helps retain juices.
Serving Suggestions
- Serve with creamy mashed potatoes and steamed green beans for a classic meat-and-potatoes dinner.
- Pair with roasted vegetables (carrots, broccoli, Brussels sprouts) and a simple side salad for a complete meal.
- Use leftovers in sandwiches: tuck a warmed slice of meatloaf into toasted bread or a bun with extra ketchup or barbecue sauce.
Tips
- Line the baking dish with parchment or foil for easier cleanup and to help lift slices out cleanly.
- Make this ahead by assembling the meat mixture in the pan, covering tightly, and refrigerating up to 24 hours before baking.
- For more flavor, sauté the onion, bell pepper, and garlic in a little oil until softened and cooled before mixing into the meat.
Prep Time:
- Prep Time: 15 minutes
- Cook Time: 1 hour
- Total Time: 1 hour 15 minutes
Nutritional Information (Per Serving)
- Calories: 320 kcal
- Protein: 20 g
- Sodium: 650 mg
Frequently Asked Questions
- Can I make this Meatloaf Casserole ahead of time?
Yes. Assemble the meat mixture in the baking dish, cover tightly, and refrigerate up to 24 hours. Add a few extra minutes to the baking time if going straight from the fridge to the oven. - Can I freeze Meatloaf Casserole?
Yes. Bake, cool completely, then wrap tightly and freeze for up to 3 months. Thaw overnight in the refrigerator and reheat, covered, at 325°F (165°C) until warmed through. - What can I use instead of breadcrumbs?
Crushed crackers, panko, or rolled oats can stand in for breadcrumbs. Use the same amount and adjust slightly if the mixture seems too wet or dry. - How do I know when the meatloaf is done?
The safest way is to use a meat thermometer inserted into the center; it should read 160°F (70°C). The juices should run mostly clear, and the top will be nicely glazed and set.
Conclusion
This Meatloaf Casserole turns a classic family favorite into an easy, oven-baked dish that’s perfect for busy evenings. With just a handful of pantry staples and a tangy-sweet glaze, it bakes up juicy, flavorful, and sliceable every time simple comfort food that makes everyone come back for seconds.
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Meatloaf Casserole
- Total Time: 1 hour 15 minutes
- Yield: 6 servings 1x
- Diet: Non-Vegetarian
Description
This Meatloaf Casserole is pure cozy comfort food a tender, juicy meatloaf base baked in a casserole dish and finished with a sweet‑savory ketchup glaze. It’s easy enough for a busy weeknight, yet satisfying and nostalgic enough to serve when you’re craving a classic homestyle dinner.
Ingredients
- 1 pound ground beef (85–90% lean)
- 1 cup breadcrumbs (plain or Italian-style
- 1/2 cup onion, finely chopped
- 1/2 cup bell pepper, finely chopped (any color)
- 2 cloves garlic, minced
- 1/2 cup milk
- 1 large egg
- 1 tablespoon Worcestershire sauce
- 1 teaspoon salt
- 1/2 teaspoon black pepper
- 1/2 teaspoon dried thyme
- 1/2 cup ketchup
- 1/4 cup brown sugar
Instructions
- Preheat your oven to 350°F (175°C). Lightly grease a 9×13-inch baking dish and set aside.
- In a large mixing bowl, combine the ground beef, breadcrumbs, onion, bell pepper, garlic, milk, egg, Worcestershire sauce, salt, black pepper, and dried thyme.
- Use clean hands or a large spoon to mix until everything is evenly combined, being careful not to overmix so the meatloaf stays tender.
- Transfer the meat mixture to the prepared baking dish and shape it into a loaf down the center, leaving space around the sides for even cooking.
- In a small bowl, stir together the ketchup and brown sugar until smooth. Spread this glaze evenly over the top of the meatloaf loaf.
- Bake in the preheated oven for about 1 hour, or until the meatloaf is cooked through and reaches an internal temperature of 160°F (70°C) in the center.
- Remove from the oven and let the meatloaf casserole rest for 10 minutes to allow the juices to redistribute.
- Slice and serve warm with your favorite sides.
Notes
- Use 85–90% lean ground beef for a balance of flavor and juiciness.
- If your mixture feels too wet, add 2–3 tablespoons more breadcrumbs; if too dry, add a splash more milk.
- Chop the onion and bell pepper finely so they soften fully while baking and blend into the meatloaf.
- You can halve the brown sugar for a less sweet glaze, or swap in honey or maple syrup.
- Prep Time: 15 minutes
- Cook Time: 1 hour
- Category: Main Course
- Method: Baked
- Cuisine: American
Nutrition
- Serving Size: 1/6 of recipe
- Calories: 320 kcal
- Sugar: 10 g
- Sodium: 650 mg
- Fat: 18 g
- Saturated Fat: 7 g
- Unsaturated Fat: 10 g
- Trans Fat: 0 g
- Carbohydrates: 18 g
- Fiber: 1 g
- Protein: 20 g
- Cholesterol: 105 mg
Keywords: meatloaf casserole, baked meatloaf, comfort food, easy dinner, ground beef casserole